牋牋This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Gene Symbol: CCL5; TCP228; SISd; MGC17164; SCYA5; RANTES; D17S136E; SIS-delta; chemokine （C-C motif） ligand 5. Gene Symbol: CCL5; TCP228; SISd; MGC17164; SCYA5; RANTES; D17S136E; SIS-delta.
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