| 英文名稱 | Anti-Cav-1（Caveolin-1） | | 中文名稱 | 抗細(xì)胞質(zhì)膜微囊蛋白-1抗體 | | | | | 產(chǎn)品類別 | 兔抗人、大、小鼠Caveolin 1抗體 | | 產(chǎn)品價格 | 0.1ml/960元 0.2ml/1200元 | | 產(chǎn)品標(biāo)準(zhǔn) | 濃縮液（1mg/1ml） 親和純化抗體 | | 產(chǎn)品應(yīng)用 | WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蠟切片需做抗原修復(fù)） | | 產(chǎn)品介紹 | 信號傳導(dǎo)（Signaling Intermediates）
Caveolin-1（小凹蛋白）是細(xì)胞生長相關(guān)信號途徑及腫瘤發(fā)生發(fā)展過程中重要的抑制因子，Caveolae是細(xì)胞膜內(nèi)的特殊膜結(jié)構(gòu)，參與包括細(xì)胞的分子運輸、細(xì)胞粘附和信號轉(zhuǎn)導(dǎo)在內(nèi)的多種細(xì)胞活動。Caveolin-1是Caveolae中重要的結(jié)構(gòu)蛋白，抑制細(xì)胞生長，與多種人類腫瘤發(fā)生發(fā)展相關(guān)的信號分子相互作用。Caveolin在信號轉(zhuǎn)導(dǎo)的整合中起支架蛋白的作用。
This is one of the five types （D1 to D5） of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is expressed in phylogenetically older regions of the brain, suggesting that it plays a role in cognitive and emotional functions. It is a target for drugs which treat schizophrenia, drug addiction, and Parkinson disease. Alternative splicing of this gene results in multiple transcript variants that would encode different isoforms, although some variants may be subject to nonsense-mediated decay （NMD）.
Also known as:
d opamine D3 receptor; 3 dopamine receptor; D ; Dopamine receptor D3; DRD; ETM1; FET1.
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