產(chǎn)品介紹 | ABCG1是ABC轉(zhuǎn)運蛋白家族中的成員,是位于組織漿膜中的單體轉(zhuǎn)運蛋白,多分布于肝、小腸、胎盤、脂肪和脾.主要用于脂質(zhì)/脂蛋白代謝與動脈粥樣硬化方面的研究。 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. |